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Anti-AQP4 Antibody (MACO0170)

SKU:
MACO0170
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Mouse
Isotype:
IgG1
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Monoclonal Antibody
Conjugation:
Unconjugated
€419
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Description

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Product Name:Anti-AQP4 Antibody
Product Sku:MACO0170
Size:100ul
Host Species:Mouse
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200
Species Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Protein
Form:Liquid
Storage Buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:Antigen Affinity Purified
Clonality:Monoclonal
Isotype:IgG1
Conjugate:Non-conjugated
Background:Aquaporin 4 belongs to the Aquaporin family of integral membrane proteins that conduct water through the cell membrane.
Synonyms:AQP-4; AQP4; aquaporin 4; aquaporin type4; Aquaporin-4; HMIWC2
UniProt Protein Function:AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described
UniProt Protein Details:

Protein type:Transporter, aquaporin family; Membrane protein, integral; Channel, misc.; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 18q11.2-q12.1

Cellular Component: basolateral plasma membrane; cytoplasm; external side of plasma membrane; integral to membrane; plasma membrane

Molecular Function:glycerol channel activity; water channel activity; water transporter activity

Biological Process: glycerol transport; multicellular organismal water homeostasis; renal water homeostasis; transmembrane transport; transport; water transport

NCBI Summary:This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]
UniProt Code:P55087
NCBI GenInfo Identifier:2506859
NCBI Gene ID:361
NCBI Accession:P55087.2
UniProt Secondary Accession:P55087,P78564,
UniProt Related Accession:P55087
Molecular Weight:32,300 Da
NCBI Full Name:Aquaporin-4
NCBI Synonym Full Names:aquaporin 4
NCBI Official Symbol:AQP4
NCBI Official Synonym Symbols:MIWC; WCH4
NCBI Protein Information:aquaporin-4
UniProt Protein Name:Aquaporin-4
UniProt Synonym Protein Names:Mercurial-insensitive water channel; MIWC; WCH4
Protein Family:Aquaporin
UniProt Gene Name:AQP4
UniProt Entry Name:AQP4_HUMAN

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