The ARHGAP11B Antibody (CAB16587) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ARHGAP11B protein, researchers can accurately detect and analyze its expression in various tissue types.ARHGAP11B, a human-specific gene derived from a retrotransposition event, has been implicated in the development of the neocortex, the part of the brain responsible for higher cognitive functions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
ARHGAP11B Antibody
SKU:
CAB16587
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
B'-T, FAM7B1, GAP (1-8), ARHGAP11B
Positive Sample:
SH-SY5Y, U-251MG
Cellular Localization:
Cytosol, Mitochondrial Matrix.
Calculated MW:
30kDa
Observed MW:
30kDa
Predicted to enable GTPase activator activity. Involved in cerebral cortex development and negative regulation of mitochondrial membrane permeability. Acts upstream of with a positive effect on glutamine catabolic process. Located in mitochondrial matrix.
Purification Method
Affinity purification
Gene ID
89839
RRID
AB_2768424
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARHGAP11B Rabbit pAb (CAB16587) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 2s.
