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Anti-RhoGAP Antibody (CAB2330)

SKU:
CAB2330
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
GFI2
RhoGAP5
p190-B
p190BRhoGAP
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

Product Name:RhoGAP Rabbit mAb
Product Code:CAB2330
Size:20uL, 50uL, 100uL
Synonyms:GFI2, RhoGAP5, p190-B, p190BRhoGAP
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human RhoGAP
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, MCF7, C2C12, Mouse brain, Rat brain
Immunogen:A synthesized peptide derived from human RhoGAP
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:394
Uniprot:Q13017
Cellular Location:Cytoplasm, Membrane, Peripheral membrane protein
Calculated MW:190kDa
Observed MW:190kDa
UniProt Protein Function:ARHGAP5: a GTPase activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP. Negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP.
UniProt Protein Details:

Protein type:GAPs; Motility/polarity/chemotaxis; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: membrane; cytoplasm; cytosol

Molecular Function:GTPase activity; protein binding; GTP binding; SH2 domain binding

Biological Process: regulation of small GTPase mediated signal transduction; mammary gland development; metabolic process; small GTPase mediated signal transduction; positive regulation of mesenchymal cell proliferation; cell adhesion; regulation of cell size; Rho protein signal transduction; positive regulation of cell migration

NCBI Summary:Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q13017
NCBI GenInfo Identifier:190358871
NCBI Gene ID:394
NCBI Accession:Q13017.2
UniProt Related Accession:Q13017
Molecular Weight:
NCBI Full Name:Rho GTPase-activating protein 5
NCBI Synonym Full Names:Rho GTPase activating protein 5
NCBI Official Symbol:ARHGAP5  
NCBI Official Synonym Symbols:GFI2; p190-B; RhoGAP5; p190BRhoGAP  
NCBI Protein Information:rho GTPase-activating protein 5
UniProt Protein Name:Rho GTPase-activating protein 5
UniProt Synonym Protein Names:Rho-type GTPase-activating protein 5; p190-B
UniProt Gene Name:ARHGAP5  
UniProt Entry Name:RHG05_HUMAN

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