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AURKA Rabbit Polyclonal Antibody (CAB15728)

SKU:
CAB15728
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle
  • Cell Cycle Antibodies 1 Anti-AURKA Antibody CAB15728
  • Cell Cycle Antibodies 1 Anti-AURKA Antibody CAB15728
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:AURKA Rabbit Polyclonal Antibody
SKU:CAB15728
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human AURKA (NP_940837.1).
Sequence:MDRS KENC ISGP VKAT APVG GPKR VLVT QQFP CQNP LPVN SGQA QRVL CPSN SSQR IPLQ AQKL VSSH KPVQ NQKQ KQLQ ATSV PHPV SRPL NNTQ KSKQ PLPS APEN NPEE ELAS KQKN EESK KRQW AL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; PPP1R47; AURKA
Positive Sample:HeLa,MCF7,HepG2
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, centriole, centrosome, cilium basal body, cytoskeleton, microtubule organizing center, spindle pole.
Calculated MW:46kDa
Observed MW:45kDa

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:6790
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using AURKA antibody (CAB15728) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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