Bavituximab Antibody is a research-grade biosimilar monoclonal antibody targeting Phosphatidylserine. It is a chimeric IgG1-kappa antibody. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer. • Phosphatidylserine and the human brain., PMID:25933483 • The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774 • Phosphatidylserine transport in cell life and death., PMID:37413778 • Phosphatidylserine., PMID:10541030 • Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225 • Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192 • Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347 • Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133 • Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986 • Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114
Product Name:
Bavituximab Antibody
SKU:
GXBS00471
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
Phosphatidylserine
Isotype:
IgG1-kappa
Host Species:
Chimeric
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
Tarvacinch3 G4, CAS: 648904-28-3
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
