Anti-BCAS2 Antibody (CAB4398)
- SKU:
- CAB4398
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BCAS2
- DAM1
- SPF27
- Snt309
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Product Name: | BCAS2 Rabbit pAb |
| Product Code: | CAB4398 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | BCAS2, DAM1, SPF27, Snt309 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1). |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, Jurkat, MCF-7, HeLa, SKOV3, Mouse testis, Mouse spleen, Mouse lung, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAGT GLVA GEVV VDAL PYFD QGYE APGV REAA AALV EEET RRYR PTKN YLSY LTAP DYSA FETD IMRN EFER LAAR QPIE LLSM KRYE LPAP SSGQ KNDI TAWQ ECVN NSMA QLEH QAVR IENL ELMS QHGC NAWK VYNE NLVH MIEH AQKE LQKL RKHI QDLN WQRK NMQL TAGS KLRE MESN WVSL VSKN YEIE RTIV QLEN EIYQ IKQQ HGEA NKEN IRQD F |
| Gene ID: | 10286 |
| Uniprot: | O75934 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 26kDa |
| Observed MW: | 25kDa |
| UniProt Protein Function: | BCAS2: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Belongs to the SPF27 family. |
| UniProt Protein Details: | Protein type:Nucleolus; RNA splicing; Spliceosome; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: nucleoplasm; spliceosome; DNA replication factor A complex; nucleolus; nucleus; cell junction Molecular Function:protein binding Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; RNA splicing; gene expression |
| UniProt Code: | O75934 |
| NCBI GenInfo Identifier: | 71153839 |
| NCBI Gene ID: | 10286 |
| NCBI Accession: | O75934.1 |
| UniProt Secondary Accession: | O75934,Q6FGS0, |
| UniProt Related Accession: | O75934 |
| Molecular Weight: | 225 |
| NCBI Full Name: | Pre-mRNA-splicing factor SPF27 |
| NCBI Synonym Full Names: | breast carcinoma amplified sequence 2 |
| NCBI Official Symbol: | BCAS2Â Â |
| NCBI Official Synonym Symbols: | DAM1; SPF27; Snt309Â Â |
| NCBI Protein Information: | pre-mRNA-splicing factor SPF27; breast carcinoma-amplified sequence 2; spliceosome-associated protein SPF 27; DNA amplified in mammary carcinoma 1 protein; spliceosome associated protein, amplified in breast cancer |
| UniProt Protein Name: | Pre-mRNA-splicing factor SPF27 |
| UniProt Synonym Protein Names: | Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated protein SPF 27 |
| UniProt Gene Name: | BCAS2Â Â |
| UniProt Entry Name: | SPF27_HUMAN |
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