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Bcl-2 Polyclonal Antibody (CAB11025)

SKU:
CAB11025
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
€129 - €359
Frequently bought together:

Description

Product Name:Bcl-2 Polyclonal Antibody
Product Code:CAB11025
Reactivity:Mouse, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:500-1:1000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Positive Samples:Mouse liver, Rat spleen
Cellular Location:Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein
Customer Validation:WB(Homo sapiens, Mus musculus, Rattus norvegicus, gallus gallus, Bos taurus)IF(Rattus norvegicus) IHC(Homo sapiens)

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-239 of human Bcl-2 (NP_000624.2).
Sequence:MAHAG RTGYD NREIV MKYIH YKLSQ RGYEW DAGDV GAAPP GAAPA PGIFS SQPGH TPHPA ASRDP VARTS PLQTP AAPGA AAGPA LSPVP PVVHL TLRQA GDDFS RRYRR DFAEM SSQLH LTPFT ARGRF ATVVE ELFRD GVNWG RIVAF FEFGG VMCVE SVNRE MSPLV DNIAL WMTEY LNRHL HTWIQ DNGGW DAFVE LYGPS MRPLF DFSWL SLKTL LSLAL VGACI TLGAY LGHK
Synonyms:Bcl-2, PPP1R50
Calculated MW:26kDa
Observed MW:26kDa

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