Bentracimab Antibody is a research-grade biosimilar monoclonal antibody targeting Ticagrelor. Format: Fab-G1-lambda (human host). Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor. • Ticagrelor., PMID:35396017 • Ticagrelor with or without Aspirin in High-Risk Patients after PCI., PMID:31556978 • Ticagrelor or Clopidogrel Monotherapy vs Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: A Systematic Review and Patient-Level Meta-Analysis., PMID:38506796 • Ticagrelor: clinical development and future potential., PMID:34258905 • Ticagrelor resistance: a case series and algorithm for management of non-responders., PMID:34215660 • Is ticagrelor worth its high cost and side-effects?, PMID:29730968 • Ticagrelor in stable coronary disease., PMID:37586825 • Ticagrelor-Associated Urticaria., PMID:35639409 • Ticagrelor Use in Stroke Patients: Past, Present, and Future., PMID:34163168 • Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome (POPular AGE): the randomised, open-label, non-inferiority trial., PMID:32334703
Product Name:
Bentracimab Antibody
SKU:
GXBS00472
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Clone:
Bentracimab
Target:
Ticagrelor
Isotype:
Fab-G1-lambda
Host Species:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
MEDI2452, anti-ticagrelor, antidote for ticagrelor, CAS: 274693-27-5
Recommended Dilutions:
ELISA: 1:2000-1:20000
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
