Description
Bevacizumab ELISA Kit
The Bevacizumab ELISA Kit (SKU: GXEL00130) is a high-sensitivity quantitative ELISA assay developed for the quantitative measurement of Bevacizumab in Plasma, Serum. The assay delivers a detection range of 312.5 - 20, 000 ng/mL and a sensitivity of 98.1 ng/mL and is read colorimetrically at 450 nm, making it well suited to quantitative research workflows.
Bevacizumab is a recombinant human IgG1 monoclonal antibody specific for all human vascular endothelial growth factor-A (VEGF-A) isoforms. The humanized anti-VEGF monoclonal antibody, bevacizumab, has been approved by the FDA as a first-line treatment for metastatic colorectal cancer in combination with chemotherapy. The pharmacokinetic properties of bevacizumab in several species have been previously described and are consistent with a typical humanized monoclonal antibody. It was shown in the literature that the surveillance of circulating concentration during maintenance therapy represents a direct and/or indirect factor for some other side effects. Identification of biomarkers for (non-)response and risk factors for adverse drug reactions that might be related to serum concentrations and maintaining the effective concentration of Bevacizumab in order to potentially avoid some side effects with a reliable method might be beneficial.
Supplied with pre-coated microplates and all core reagents, the Bevacizumab ELISA Kit gives you a validated, ready-to-use solution for Bevacizumab research. Get accurate and reliable results with the Bevacizumab ELISA Kit from Assay Genie.
| Product Name: | Bevacizumab ELISA Kit |
| SKU: | GXEL00130 |
| Accession: | P15692 |
| Alternative Names: | 12-IgG1, F(ab)-12 IgG1, Fab-12 IgG1, rhuMAb-VEGF, ABP 215, 216974-75-3 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 98.1 ng/mL |
| Range: | 312.5 - 20, 000 ng/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 98.1 ng/mL |
| Detection Range | 312.5 - 20, 000 ng/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20°C, the rest reagents should be store at 4°C.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
