Bexmarilimab Antibody is a research-grade biosimilar monoclonal antibody targeting MS-1 antigen. It is a humanized IgG4-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Stabilin-1 (STAB1) is a ~275 kDa protein. Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.
Product Name:
Bexmarilimab Antibody
SKU:
GXBS00466
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
MS-1 antigen
Isotype:
IgG4-kappa
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FCM, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
MS-1 antigen, STAB1, FEEL-1, FEEL1, Stabilin-1, KIAA0246, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.