Biciromab Antibody is a research-grade biosimilar monoclonal antibody targeting FGB. It is a mouse IgG1-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays, in vivo research and Western blot. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Fibrinogen beta chain (FGB) is a ~55 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.
Product Name:
Biciromab Antibody
SKU:
GXBS00331
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
FGB
Isotype:
IgG1-kappa
Host Species:
Mouse
Reactivity:
Human
Applications:
ELISA, FCM, Functional assay, Research in vivo, WB
Expression Host:
Mammalian cells
Synonyms:
Indium(111In)biciromab, T2G1, 138783-13-8
Recommended Dilutions:
ELISA: 1:2000-1:20000; WB: 1:500-1:2000
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
