Description
Product Title: | Biotin Anti-Mouse TCR γ/δ Antibody [GL3] |
SKU: | AGEL3298 |
Size: | 25µg, 100µg |
Clone No: | GL3 |
Synonyms: | T cell receptor γ/δ; |
Host Species: | Syrian Hamster |
Reactivity: | Human;Mouse |
Application: | FCM |
Isotype: | Armenian Hamster IgG |
Isotype Control: | Biotin Armenian Hamster IgG Isotype Control[PIP] |
Form: | Liquid |
Conjugation: | Biotin |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | Q96E93 O88713 |
Gene ID: | 110066,110067 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. |