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Anti-CAMP Antibody (CAB1640)

SKU:
CAB1640
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 7 Anti-CAMP Antibody CAB1640
  • Cell Biology Antibodies 7 Anti-CAMP Antibody CAB1640
  • Cell Biology Antibodies 7 Anti-CAMP Antibody CAB1640
  • Cell Biology Antibodies 7 Anti-CAMP Antibody CAB1640
  • Cell Biology Antibodies 7 Anti-CAMP Antibody CAB1640
€139 - €419
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Description

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Antibody Name:Anti-CAMP Antibody
Antibody SKU:CAB1640
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human CAMP (NP_004336.3).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:MCF7, SGC-7901, A-549, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human CAMP (NP_004336.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IIAQ VLSY KEAV LRAI DGIN QRSS DANL YRLL DLDP RPTM DGDP DTPK PVSF TVKE TVCP RTTQ QSPE DCDF KKDG LVKR CMGT VTLN QARG SFDI SCDK DNKR FALL GDFF RKSK EKIG KEFK RIVQ RIKD FLRN LVPR
Gene ID:820
Uniprot:P49913
Cellular Location:Secreted
Calculated MW:19kDa
Observed MW:19kDa
Synonyms:CAMP, CAP-18, CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37
Background:This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation.
UniProt Protein Function:CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Cell cycle regulation; Vesicle; Secreted

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cell wall; extracellular region; extracellular space; specific granule

Biological Process: antibacterial humoral response; cell redox homeostasis; defense response to bacterium; defense response to Gram-positive bacterium; innate immune response in mucosa; killing by host of symbiont cells

NCBI Summary:This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]
UniProt Code:P49913
NCBI GenInfo Identifier:1706745
NCBI Gene ID:820
NCBI Accession:P49913.1
UniProt Secondary Accession:P49913,Q71SN9,
UniProt Related Accession:P49913
Molecular Weight:19,301 Da
NCBI Full Name:Cathelicidin antimicrobial peptide
NCBI Synonym Full Names:cathelicidin antimicrobial peptide
NCBI Official Symbol:CAMP  
NCBI Official Synonym Symbols:LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39  
NCBI Protein Information:cathelicidin antimicrobial peptide
UniProt Protein Name:Cathelicidin antimicrobial peptide
UniProt Synonym Protein Names:FALL-39 peptide antibiotic
Protein Family:CAMPATH-1 antigen
UniProt Gene Name:CAMP  
UniProt Entry Name:CAMP_HUMAN
Anti-CAMP Antibody (CAB1640)Western blot analysis of extracts of various cell lines, using CAMP Antibody (CAB1640) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
Anti-CAMP Antibody (CAB1640)Immunohistochemistry of paraffin-embedded mouse testis using CAMP antibody (CAB1640) at dilution of 1:200 (40x lens).
Anti-CAMP Antibody (CAB1640)Immunohistochemistry of paraffin-embedded human lung using CAMP antibody (CAB1640) at dilution of 1:200 (40x lens).
Anti-CAMP Antibody (CAB1640)Immunohistochemistry of paraffin-embedded mouse spleen using CAMP antibody (CAB1640) at dilution of 1:200 (40x lens).
Anti-CAMP Antibody (CAB1640)Immunohistochemistry of paraffin-embedded human tonsil using CAMP antibody (CAB1640) at dilution of 1:200 (40x lens).

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