The CARD14 Antibody (CAB16569) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit sources, is specifically reactive with human samples and has been validated for use in Western blot applications. By targeting the CARD14 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in immunology, dermatology, and inflammatory diseases.CARD14 is a key player in the signaling pathways that control immune and inflammatory responses in the skin, making it a target of interest in research on conditions like psoriasis and inflammatory skin disorders.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CARD14 Antibody
SKU:
CAB16569
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PRP, PSS1, BIMP2, CARMA2, PSORS2, CARD14
Positive Sample:
HT-29, HeLa
Cellular Localization:
Cytoplasm, Cytoplasm.
Calculated MW:
113kDa
Observed MW:
113kDa
This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
79092
RRID
AB_2768714
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CARD14 Rabbit pAb (CAB16569) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
