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CD119 Polyclonal Antibody (CAB23652)

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SKU CAB23652
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Mouse
Host Species Rabbit
Synonyms Ifgr, CD119, Ifngr, Nktar, IFN-gammaR
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Description

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CD119 Polyclonal Antibody (CAB23652)

The CD119 Polyclonal Antibody (CAB23652) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications. By targeting the CD119 protein, researchers can accurately detect and analyze its presence in various cell types, facilitating investigations in immunology and cancer research.CD119, also known as an inhibitory receptor, plays a crucial role in immune modulation by regulating inflammatory responses and suppressing allergic reactions. Its importance in immune homeostasis highlights its relevance in the study of diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.

Product Name:CD119 Polyclonal Antibody
SKU:CAB23652
Size:20μL, 100μL
Reactivity:Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:Email for sequence
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:5000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:Ifgr, CD119, Ifngr, Nktar, IFN-gammaR
Positive Sample:EL4
Calculated MW:52kDa
Observed MW:70-95kDa

Predicted to enable cytokine receptor activity. Involved in several processes, including astrocyte activation; negative regulation of amyloid-beta clearance; and positive regulation of macromolecule metabolic process. Acts upstream of or within defense response to virus. Predicted to be located in several cellular components, including dendrite; endoplasmic reticulum; and postsynaptic density. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; cerebral cortex; cranium; female reproductive system; and liver. Used to study osteoporosis. Human ortholog(s) of this gene implicated in asthma; hepatitis B; immunodeficiency 27A; immunodeficiency 27B; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1).

Purification MethodAffinity purification
Gene ID15979
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from EL4 cells, using CD119 Rabbit pAb (CAB23652) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.

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