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Anti-Cadherin 16 Antibody (CAB19644)

SKU:
CAB19644
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139
Frequently bought together:

Description

Product Name:Cadherin 16 Rabbit mAb
Product Code:CAB19644
Size:20uL, 50uL, 100uL
Applications:WB, IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Cadherin 16
Applications:WB, IF
Recommended Dilutions:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:Mouse kidney
Immunogen:A synthesized peptide derived from human Cadherin 16
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:1014
Uniprot:O75309
Calculated MW:120kDa
Observed MW:120KDa
UniProt Protein Function:CDH16: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q22.1

Biological Process: cell adhesion

NCBI Summary:This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
UniProt Code:O75309
NCBI GenInfo Identifier:13431340
NCBI Gene ID:1014
NCBI Accession:O75309.1
UniProt Secondary Accession:O75309,Q6UW93, B4DPA8, H3BPD3,
UniProt Related Accession:O75309
Molecular Weight:85,774 Da
NCBI Full Name:Cadherin-16
NCBI Synonym Full Names:cadherin 16
NCBI Official Symbol:CDH16  
NCBI Protein Information:cadherin-16
UniProt Protein Name:Cadherin-16
UniProt Synonym Protein Names:Kidney-specific cadherin; Ksp-cadherin
Protein Family:Cadherin
UniProt Gene Name:CDH16  
UniProt Entry Name:CAD16_HUMAN

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