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CDw131 monoclonal antibody (AGIM0003)

SKU:
AGIM0003
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1,k
Clone:
1C1
Conjugation:
Unconjugated
Applications:
FC
€179
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Description

system_update_altDatasheet
Product Name:CDw131 monoclonal antibody
Product Code:AGIM0003
Size:100 µg in 100 µL
Reactivity:Human
Clone:1C1
Applications:Flow Cytometry
Conjugate:Unconjugated
Isotype:IgG1,k
Host Species:Mouse
Storage:Store at -20°C.
Uniprot:P32927
UniProt Protein Function:CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.
UniProt Protein Details:

Protein type:Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane

Molecular Function:interleukin-3 receptor activity; interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor activity

Biological Process: cellular protein metabolic process; MAPKKK cascade; respiratory gaseous exchange

Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5

NCBI Summary:The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
UniProt Code:P32927
NCBI GenInfo Identifier:1345923
NCBI Gene ID:1439
NCBI Accession:P32927.2
UniProt Secondary Accession:P32927,Q5JZI1, Q6ICE0,
UniProt Related Accession:P32927
Molecular Weight:97,976 Da
NCBI Full Name:Cytokine receptor common subunit beta
NCBI Synonym Full Names:colony stimulating factor 2 receptor beta common subunit
NCBI Official Symbol:CSF2RB  
NCBI Official Synonym Symbols:CD131; IL3RB; IL5RB; SMDP5; CDw131  
NCBI Protein Information:cytokine receptor common subunit beta
UniProt Protein Name:Cytokine receptor common subunit beta
UniProt Synonym Protein Names:CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131
Protein Family:Cytokine receptor
UniProt Gene Name:CSF2RB  
UniProt Entry Name:IL3RB_HUMAN

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