The CEACAM3 Antibody (CAB2589) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CEACAM3, also known as carcinoembryonic antigen-related cell adhesion molecule 3, plays a crucial role in immune surveillance and host defense mechanisms. By targeting CEACAM3, researchers can investigate its functions in immune cell interactions, microbial recognition, and inflammation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
CEACAM3 Antibody
SKU:
CAB2589
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CEA, CGM1, W264, W282, CD66D, CD66d/CEACAM3
Positive Sample:
A-549, Mouse spleen
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
27kDa
Observed MW:
33kDa
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
Purification Method
Affinity purification
Gene ID
1084
RRID
AB_2764474
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from A549 cells, using CEACAM3 (CAB2589) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
