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CES1 Rabbit Polyclonal Antibody (CAB1853)

SKU:
CAB1853
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
  • Cell Biology Antibodies 7 Anti-CES1 Antibody CAB1853
  • Cell Biology Antibodies 7 Anti-CES1 Antibody CAB1853
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CES1 Rabbit Polyclonal Antibody
SKU:CAB1853
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 287-566 of human CES1 (NP_001257.4).
Sequence:RQKT EEEL LETT LKMK FLSL DLQG DPRE SQPL LGTV IDGM LLLK TPEE LQAE RNFH TVPY MVGI NKQE FGWL IPML MSYP LSEG QLDQ KTAM SLLW KSYP LVCI AKEL IPEA TEKY LGGT DDTV KKKD LFLD LIAD VMFG VPSV IVAR NHRD AGAP TYMY EFQY RPSF SSDM KPKT VIGD HGDE LFSV FGAP FLKE GASE EEIR LSKM VMKF WANF ARNG NPNG EGLP HWPE YNQK EGYL QIGA NTQA AQKL KDKE VAFW TNLF AKKA VEKP PQTE HIEL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:CEH; REH; TGH; ACAT; CE-1; CES2; HMSE; SES1; HMSE1; PCE-1; hCE-1; CES1
Positive Sample:Mouse liver,A-549,U-937
Conjugate:Unconjugated
Cellular Localization:Endoplasmic reticulum lumen.
Calculated MW:63kDa
Observed MW:63kDa

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:1066
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CES1 Rabbit pAb (CAB1853) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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