The CLDND1 Antibody (CAB2945) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, shows high specificity and sensitivity for CLDND1 in human samples, making it a reliable choice for Western blot applications.CLDND1, also known as claudin domain containing 1, plays a crucial role in maintaining the integrity of tight junctions between cells, which are essential for controlling the passage of molecules and ions across epithelial and endothelial barriers. Dysregulation of CLDND1 has been linked to various diseases, including cancer and inflammatory disorders, highlighting its importance in cellular function and disease pathology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
CLDND1 Antibody
SKU:
CAB2945
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Z38, C3orf4, GENX-3745, CLDND1
Positive Sample:
Mouse brain, Mouse kideny, Rat brain
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
29kDa
Observed MW:
29kDa
Located in cell surface.
Purification Method
Affinity purification
Gene ID
56650
RRID
AB_2764759
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CLDND1 Rabbit pAb (CAB2945) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
