The MMP10 Antibody (CAB3033) is a high-quality antibody developed for reliable detection and analysis of target proteins. Stromelysin-2, also known as matrix metalloproteinase-10 (MMP-10), is a key enzyme involved in matrix remodeling and tissue repair.This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the Stromelysin-2 protein, this antibody enables the detection and analysis of Stromelysin-2 in different cell types and tissues.Stromelysin-2 has been implicated in various pathologies, including cancer metastasis, arthritis, and tissue fibrosis.
This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MMP10 Antibody
SKU:
CAB3033
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.
Purification Method
Affinity purification
Gene ID
4319
RRID
AB_2764839
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MMP10 Rabbit pAb (CAB3033) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry analysis of paraffin-embedded Rat kidney using MMP10 Rabbit pAb (CAB3033) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Immunofluorescence analysis of NIH-3T3 cells using MMP10 Rabbit pAb (CAB3033) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
