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Anti-COPG2 Antibody (CAB15817)

SKU:
CAB15817
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 6 Anti-COPG2 Antibody CAB15817
  • Cell Biology Antibodies 6 Anti-COPG2 Antibody CAB15817
  • Cell Biology Antibodies 6 Anti-COPG2 Antibody CAB15817
€139 - €419
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Description

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Antibody Name:Anti-COPG2 Antibody
Antibody SKU:CAB15817
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_036265.3).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse heart, Mouse kidney, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_036265.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LNAT YIFN GLTV SVPG MEKA LHQY TLEP SEKP FDMK SIPL AMAP VFEQ KAEI TLVA TKPE KLAP SRQD IFQE QLAA IPEF LNIG PLFK SSEP VQLT EAET EYFV RCIK HMFT NHIV FQFD CTNT LNDQ LLEK VTVQ MEPS DSYE VLSC IPAP SLPY NQPG ICYT LVRL PDDD PTAV AGSF SCTM KFTV RDCD PNTG VPDE DGYD DEYV LEDL EVTV SDHI QKVL KPNF AAAW EEVG DTFE KEET FALS STKT LEEA VNNI ITFL GMQP CERS DKVP ENKN SHSL YLAG IFRG GYDL LVRS RLAL ADGV TMQV TVRS KERT PVDV ILAS VG
Gene ID:26958
Uniprot:Q9UBF2
Cellular Location:COPI-coated vesicle membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus membrane, Peripheral membrane protein, cytosol
Calculated MW:81kDa/97kDa
Observed MW:105kDa
Synonyms:COPG2, 2-COP, gamma-2-COP
Background:
UniProt Protein Function:COPG2: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Belongs to the COPG family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Vesicle

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: COPI vesicle coat; cytosol

Molecular Function:structural molecule activity

Biological Process: intra-Golgi vesicle-mediated transport; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER

UniProt Code:Q9UBF2
NCBI GenInfo Identifier:13124090
NCBI Gene ID:26958
NCBI Accession:Q9UBF2.1
UniProt Related Accession:Q9UBF2
Molecular Weight:Calculated: 81kDa; 97kDaObserved: 105kDa
NCBI Full Name:Coatomer subunit gamma-2
NCBI Synonym Full Names:coatomer protein complex subunit gamma 2
NCBI Official Symbol:COPG2  
NCBI Official Synonym Symbols:2-COP; gamma-2-COP  
NCBI Protein Information:coatomer subunit gamma-2
UniProt Protein Name:Coatomer subunit gamma-2
UniProt Synonym Protein Names:Gamma-2-coat protein; Gamma-2-COP
Protein Family:Coatomer
UniProt Gene Name:COPG2  
UniProt Entry Name:COPG2_HUMAN
Anti-COPG2 Antibody (CAB15817)Western blot analysis of extracts of various cell lines, using COPG2 antibody (CAB15817) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-COPG2 Antibody (CAB15817)Immunohistochemistry of paraffin-embedded mouse brain using COPG2 antibody (CAB15817) at dilution of 1:100 (40x lens).
Anti-COPG2 Antibody (CAB15817)Immunofluorescence analysis of U-2 OS cells using COPG2 Polyclonal Antibody (CAB15817) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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