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Anti-Cpn10 Antibody (CAB5580)

SKU:
CAB5580
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
$167 - $503
Frequently bought together:

Description

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Antibody Name:Anti-Cpn10 Antibody
Antibody SKU:CAB5580
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Cpn10
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:MCF7, C6, U-251MG, Neuro-2a, Rat kidney
Immunogen:A synthesized peptide derived from human Cpn10
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3336
Uniprot:P61604
Cellular Location:
Calculated MW:11kDa
Observed MW:11KDa
Synonyms:CPN10, EPF, GROES, HSP10
Background:This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
UniProt Protein Function:HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family.
UniProt Protein Details:

Protein type:Mitochondrial

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: membrane; mitochondrial matrix; mitochondrion

Molecular Function:ATP binding; chaperone binding; protein binding; unfolded protein binding

Biological Process: caspase activation; osteoblast differentiation; protein folding; response to unfolded protein

NCBI Summary:This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
UniProt Code:P61604
NCBI GenInfo Identifier:47606335
NCBI Gene ID:3336
NCBI Accession:P61604.2
UniProt Secondary Accession:P61604,O95421, Q04984, Q53X54, Q9UDH0,
UniProt Related Accession:P61604
Molecular Weight:10,932 Da
NCBI Full Name:10 kDa heat shock protein, mitochondrial
NCBI Synonym Full Names:heat shock protein family E (Hsp10) member 1
NCBI Official Symbol:HSPE1  
NCBI Official Synonym Symbols:EPF; CPN10; GROES; HSP10  
NCBI Protein Information:10 kDa heat shock protein, mitochondrial
UniProt Protein Name:10 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names:10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
UniProt Gene Name:HSPE1  
UniProt Entry Name:CH10_HUMAN
Anti-Cpn10 Antibody (CAB5580)Western blot - Cpn10 Rabbit mAb (CAB5580)

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