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CREB1 Rabbit Polyclonal Antibody (CAB11989)

SKU:
CAB11989
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 2 Anti-CREB1 Antibody CAB11989
  • Cell Biology Antibodies 2 Anti-CREB1 Antibody CAB11989
  • Cell Biology Antibodies 2 Anti-CREB1 Antibody CAB11989
  • Cell Biology Antibodies 2 Anti-CREB1 Antibody CAB11989
  • Cell Biology Antibodies 2 Anti-CREB1 Antibody CAB11989
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CREB1 Rabbit Polyclonal Antibody
SKU:CAB11989
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CREB1 (NP_604391.1).
Sequence:MTME SGAE NQQS GDAA VTEA ENQQ MTVQ AQPQ IATL AQVS MPAA HATS SAPT VTLV QLPN GQTV QVHG VIQA AQPS VIQS PQVQ TVQS SCKD LKRL FSGT QIST IAES EDSQ ESVD SVTD SQKR REIL SRRP SYRK ILND LSSD APGV PRIE EEKS EEET SAPA ITTV TVPT PIYQ TSSG QYIA ITQG GAIQ LANN GTDG VQGL QTLT MTNA AATQ PGTT ILQY AQTT DGQQ ILVP SNQV VVQA ASGD VQTY QIRT APTS TIAP GVVM ASSP ALPT QPAE EAAR KREV RLMK NREA AREC RRKK KEYV KCLE NRVA VLEN QNKT LIEE LKAL KDLY CHKS D
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:CREB; CREB-1; CREB1
Positive Sample:HeLa,Jurkat,C6
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:35kDa

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:1385
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CREB1 Rabbit pAb (CAB11989) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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