100% Quality Guarantee
PhD-Level Technical Support
Key Features

Cystatin C Rabbit Monoclonal Antibody (CAB8933)

Datasheet MSDS
SKU CAB8933
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms ARMD11, HEL-S-2, Cystatin C
Research Use Cell Biology
€131 - €457

Request a formal quotation

A PDF quote with its own quote number, ready for your purchasing office to raise a PO against. Back within 4 working hours, from a PhD scientist — not an autoresponder.

  • PO-ready PDFQuote number, VAT, Incoterms
  • Volume pricing appliedDiscounts from 2 kits up
  • Valid 30 daysPrices held while you get sign-off
Anything we should know? optional

No account needed. We use your details only to prepare and send this quote. If it's urgent, say so in the box and we'll come back the same working day.
Global Shipping: 80+ Countries
White Glove Service: Available upon request
Batch Consistency: Contact Sales
Distributors: 60+ Countries
Contact Sales Quote or discount
Find Distributor 50+ countries
Technical Support PhD-level team
Live Chat Available now

Description

system_update_altDatasheetsystem_update_altMSDS

Cystatin C Monoclonal Antibody (CAB8933)

The Cystatin C Monoclonal Antibody (CAB8933) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody has been specifically raised in rabbits and is highly reactive with human samples, making it ideal for use in a variety of research applications.Cystatin C is a cysteine proteinase inhibitor that is primarily produced by nucleated cells and is involved in regulating enzyme activity. It has been shown to be a reliable marker for kidney function, with levels in the blood correlating with glomerular filtration rate. Additionally, Cystatin C has been implicated in various disease processes, including cardiovascular disease, diabetes, and neurodegenerative disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Cystatin C Monoclonal Antibody
SKU:CAB8933
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC1357
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAGP LRAP LLLL AILA VALA VSPA AGSS PGKP PRLV GGPM DASV EEEG VRRA LDFA VGEY NKAS NDMY HSRA LQVV RARK QIVA GVNY FLDV ELGR TTCT KTQP NLDN CPFH DQPH LKRK AFCS FQIY AVPW QGTM TLSK STCQ DA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ARMD11, HEL-S-2, Cystatin C
Positive Sample:Human plasma, HeLa, SH-SY5Y, Mouse lung,
Cellular Localization:Secreted.
Calculated MW:13kDa
Observed MW:15kDa

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.

Purification MethodAffinity purification
Gene ID1471
RRIDAB_2863631
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Cystatin C Rabbit mAb (CAB8933) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageWestern blot analysis of various lysates using Cystatin C Rabbit mAb (CAB8933) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
View AllClose

0 Reviews

Write a Review
0
Based on 0 reviews

No reviews yet. Be the first to share your experience!

View AllClose

Related Products