Datopotamab Antibody (Datopotamab Deruxtecan ADC, Payload-Free) is a research-grade biosimilar monoclonal antibody targeting Pancreatic carcinoma marker protein GA733-1. It is a humanized IgG1-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Supplied as the antibody component without the cytotoxic payload. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Tumor-associated calcium signal transducer 2 (TACSTD2/TROP2) is a ~35 kDa protein. May function as a growth factor receptor. TACSTD2 is the therapeutic target of sacituzumab govitecan (Trodelvy).