DCK Rabbit Polyclonal Antibody (CAB1794)
- SKU:
- CAB1794
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DCK Rabbit Polyclonal Antibody |
SKU: | CAB1794 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1). |
Sequence: | MATP PKRS CPSF SASS EGTR IKKI SIEG NIAA GKST FVNI LKQL CEDW EVVP EPVA RWCN VQST QDEF EELT MSQK NGGN VLQM MYEK PERW SFTF QTYA CLSR IRAQ LASL NGKL KDAE KPVL FFER SVYS DRYI FASN LYES ECMN ETEW TIYQ DWHD WMNN QFGQ SLEL DGII YLQA TPET CLHR IYLR GRNE EQGI PLEY LEKL HYKH ESWL LHRT LKTN FDYL QEVP ILTL DVNE DFKD KYES LVEK VKEF LSTL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | DCK |
Positive Sample: | 293F,Mouse brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 31kDa |
Observed MW: | 31kDa |
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Purification Method: | Affinity purification |
Gene ID: | 1633 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |