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DMRT1 Rabbit Polyclonal Antibody (CAB8411)

SKU:
CAB8411
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:DMRT1 Rabbit Polyclonal Antibody
SKU:CAB8411
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 134-373 of human DMRT1 (NP_068770.2).
Sequence:SHPI PLPS AAEL LVKR ENNG SNPC LMTE CSGT SQPP PASV PTTA ASEG RMVI QDIP AVTS RGHV ENTP DLVS DSTY YSSF YQPS LFPY YNNL YNCP QYSM ALAA DSAS GEVG NPLG GSPV KNSL RGLP GPYV PGQT GNQW QMKN MENR HAMS SQYR MHSY YPPP SYLG QSVP QFFT FEDA PSYP EARA SVFS PPSS QDSG LVSL SSSS PISN KSTK AVLE CEPA SEPS SFTV TPVI EEDE
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:DMT1; CT154; DMRT1
Positive Sample:U-937
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:39kDa
Observed MW:39kDa

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Purification Method:Affinity purification
Gene ID:1761
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using DMRT1 Rabbit pAb (CAB8411) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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