UniProt Protein Function: | DOCK5: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; Motility/polarity/chemotaxis; GAPsChromosomal Location of Human Ortholog: 8p21.2Cellular Component: cytoplasmMolecular Function: guanyl-nucleotide exchange factor activityBiological Process: positive regulation of GTPase activity; positive regulation of smooth muscle cell migration; small GTPase mediated signal transduction |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9H7D0 |
NCBI GenInfo Identifier: | 117553586 |
NCBI Gene ID: | 80005 |
NCBI Accession: | NP_079216.4 |
UniProt Secondary Accession: | Q9H7D0,Q5XKD5, Q6AI11, Q6PJS6, Q6ZTS6, B2RNY0 |
UniProt Related Accession: | Q9H7D0 |
Molecular Weight: | 40,421 Da |
NCBI Full Name: | dedicator of cytokinesis protein 5 |
NCBI Synonym Full Names: | dedicator of cytokinesis 5 |
NCBI Official Symbol: | DOCK5Â Â |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | dedicator of cytokinesis protein 5 |
UniProt Protein Name: | Dedicator of cytokinesis protein 5 |
UniProt Synonym Protein Names: | |
Protein Family: | Dedicator of cytokinesis protein |
UniProt Gene Name: | DOCK5Â Â |
UniProt Entry Name: | DOCK5_HUMAN |