Efaprinermin Alfa (Research-Grade) is a research-grade biosimilar antibody targeting CD357. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Product Name:
Efaprinermin Alfa (Research-Grade)
SKU:
GXBS01197
Size:
100 µg, 1 mg
Target:
Activation-inducible TNFR family receptor
Isotype:
Fusion - [TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2 - IGHG1 Fc (Fragment constant)
Reactivity:
Human
Applications:
ELISA, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
OMP-336B11, 2102200-64-4
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Chimeric IgG4-kappa anti-(human complement C3d) fused at the C-terminus of the heavy chain, via a (G4S)2 peptide linker to human complement factor H fragment.
