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Efgivanermin Alfa (Research-Grade) - SDS-PAGE
Key Features

Efgivanermin Alfa (Research-Grade) (GXBS01199)

Datasheet MSDS
SKU GXBS01199
Product Type Research Grade Biosimilar
Reactivity Human
Applications ELISA, Functional assay, Research in vivo
Isotype Fusion - [IGHG1 Fc (Fragment constant) - [CORO1A (coronin 1A, actin-binding protein) - TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2]3 (hexamer)
$751 - $2,507

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Description

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Efgivanermin Alfa (Research-Grade)

Efgivanermin Alfa (Research-Grade) is a research-grade biosimilar antibody targeting CD357. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Product Name:Efgivanermin Alfa (Research-Grade)
SKU:GXBS01199
Size:100 µg, 1 mg
Target:Activation-inducible TNFR family receptor
Isotype:Fusion - [IGHG1 Fc (Fragment constant) - [CORO1A (coronin 1A, actin-binding protein) - TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2]3 (hexamer)
Reactivity:Human
Applications:ELISA, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:MEDI-1873, MEDI1873, 1807864-13-6
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:Q9Y5U5
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