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Eftansomatropin alfa (Research-Grade)
Key Features

Eftansomatropin alfa (Research-Grade) (GXBS02704)

Datasheet MSDS
SKU GXBS02704
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications Functional assay
Isotype GH1-IGHG4 Fc
€513 - €1,677

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Description

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Eftansomatropin alfa (Research-Grade)

Eftansomatropin alfa (Research-Grade) is a research-grade biosimilar monoclonal antibody targeting Growth hormone receptor. Format: GH1-IGHG4 Fc (human host). Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: functional assays. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.

Growth hormone receptor (GHR) is a ~71 kDa protein. Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. 1. de Vos, AM. et al. (1992) Science (New York, N.Y.) 255, 306-12. PMID: 1549776 2. Leung, DW. et al. (1987) Nature 330, 537-43. PMID: 2825030 3. Sundström, M. et al. (1996) The Journal of biological chemistry 271, 32197-203. PMID: 8943276 4. Greenhalgh, CJ. et al. (2005) The Journal of clinical investigation 115, 397-406. PMID: 15690087

Product Name:Eftansomatropin alfa (Research-Grade)
SKU:GXBS02704
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Target:Growth hormone receptor
Isotype:GH1-IGHG4 Fc
Host Species:Human
Reactivity:Human
Applications:Functional assay
Synonyms:Growth hormone receptor, GH receptor, Somatotropin receptor, Growth hormone-binding protein, GH-binding protein, GHBP, Serum-binding protein, GHR
Purity:>95% as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:P10912
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