Efungumab Antibody is a research-grade biosimilar monoclonal antibody targeting HSP90. Format: scFv-heavy-kappa (human host). Reactivity: Candida albicans. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Heat shock protein 90 homolog (HSP90) is a ~80 kDa protein. Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Product Name:
Efungumab Antibody
SKU:
GXBS00487
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
HSP90
Isotype:
scFv-heavy-kappa
Host Species:
Human
Reactivity:
Candida albicans
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
HSP90mab, Mycograb, 762260-74-2
Recommended Dilutions:
ELISA: 1:2000-1:20000
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.