The EphB6 Polyclonal Antibody (CAB14729) is an essential tool for researchers studying the EphB6 receptor, a member of the Eph receptor family known for its role in various biological processes, including cell adhesion, migration, and tissue development. This antibody, produced through rabbit immunization, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blotting applications.EphB6 is a transmembrane protein that plays a crucial role in cell signaling and communication, particularly in regulating cell-cell interactions and tissue patterning.
Dysregulation of EphB6 expression has been linked to various diseases, including cancer, neurological disorders, and cardiovascular conditions. By targeting EphB6 with this antibody, researchers can gain insights into its function and potential therapeutic implications in these pathological contexts.Overall, the EphB6 Polyclonal Antibody (CAB14729) offers a valuable tool for studying EphB6 biology and exploring its potential as a therapeutic target in multiple disease settings, providing a platform for cutting-edge research in molecular biology and drug development.
Product Name:
EPHB6 Rabbit Polyclonal Antibody
SKU:
CAB14729
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 615-729 of human EPHB6 (NP_001267724.2).
Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
111kDa
Observed MW:
111kDa
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2051
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EPHB6 Rabbit pAb (CAB14729) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
