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IL6 Rabbit Polyclonal Antibody (CAB0286)

SKU:
CAB0286
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-IL-6 Antibody CAB0286
  • Immunology Antibodies 1 Anti-IL-6 Antibody CAB0286
  • Immunology Antibodies 1 Anti-IL-6 Antibody CAB0286
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:IL6 Rabbit Polyclonal Antibody
SKU:CAB0286
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 30-212 of human IL6 (NP_000591.1).
Sequence:VPPG EDSK DVAA PHRQ PLTS SERI DKQI RYIL DGIS ALRK ETCN KSNM CESS KEAL AENN LNLP KMAE KDGC FQSG FNEE TCLV KIIT GLLE FEVY LEYL QNRF ESSE EQAR AVQM STKV LIQF LQKK AKNL DAIT TPDP TTNA SLLT KLQA QNQW LQDM TTHL ILRS FKEF LQSS LRAL RQM
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; IL6
Positive Sample:HUVEC
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:24kDa
Observed MW:24kDa

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).

Purification Method:Affinity purification
Gene ID:3569
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using IL6 Rabbit pAb (CAB0286) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

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