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Anti-ErbB4 Antibody (CAB19047)

SKU:
CAB19047
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ErbB4 Antibody
Antibody SKU:CAB19047
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human ErbB4
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse brain
Immunogen:A synthesized peptide derived from human ErbB4
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2066
Uniprot:Q15303
Cellular Location:
Calculated MW:160kDa
Observed MW:160kDa
Anti-ErbB4 Antibody (CAB19047)Western blot - ErbB4 Rabbit mAb (CAB19047)
Synonyms:ALS19, HER4, p180erbB4, ERBB4, HER4/ErbB4
Background:This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
NCBI Summary:This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
UniProt Code:Q15303
NCBI GenInfo Identifier:3913590
NCBI Gene ID:2066
NCBI Accession:
UniProt Related Accession:Q15303
Molecular Weight:
NCBI Full Name:Receptor tyrosine-protein kinase erbB-4
NCBI Synonym Full Names:erb-b2 receptor tyrosine kinase 4
NCBI Official Symbol:ERBB4  
NCBI Official Synonym Symbols:HER4; ALS19; p180erbB4  
NCBI Protein Information:receptor tyrosine-protein kinase erbB-4
UniProt Protein Name:
UniProt Gene Name:

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