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Anti-Pea3 / ETV4 Antibody (CAB5797)

SKU:
CAB5797
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-Pea3 / ETV4 Antibody CAB5797
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-Pea3 / ETV4 Antibody CAB5797
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-Pea3 / ETV4 Antibody CAB5797
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-Pea3 / ETV4 Antibody CAB5797
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-Pea3 / ETV4 Antibody CAB5797
€139 - €419
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Description

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Antibody Name:Anti-Pea3 / ETV4 Antibody
Antibody SKU:CAB5797
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human Pea3 / ETV4 (NP_001248368.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:SW480, Mouse stomach, Mouse heart, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human Pea3 / ETV4 (NP_001248368.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MYLH TEGF SGPS PGDG AMGY GYEK PLRP FPDD VCVV PEKF EGDI KQEG VGAF REGP PYQR RGAL QLWQ FLVA LLDD PTNA HFIA WTGR GMEF KLIE PEEV ARLW GIQK NRPA MNYD KLSR SLRY YYEK GIMQ KVAG ERYV YKFV CEPE ALFS LAFP DNQR PALK AEFD RPVS EEDT VPLS HLDE SPAY LPEL AGPA QPFG PKGG YSY
Gene ID:2118
Uniprot:P43268
Cellular Location:Nucleus
Calculated MW:23kDa/49kDa/53kDa
Observed MW:54KDa
Synonyms:ETV4, E1A-F, E1AF, PEA3, PEAS3, ETS variant 4, Pea3/ETV4
Background:
UniProt Protein Function:ETV4: Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. Belongs to the ETS family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: nucleolus

Molecular Function:protein binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; motor axon guidance; stem cell differentiation; cell differentiation; negative regulation of mammary gland epithelial cell proliferation

UniProt Code:P43268
NCBI GenInfo Identifier:62512145
NCBI Gene ID:2118
NCBI Accession:P43268.3
UniProt Secondary Accession:P43268,Q96AW9, A8K314, B7Z5J3, B7Z9J6,
UniProt Related Accession:P43268
Molecular Weight:484
NCBI Full Name:ETS translocation variant 4
NCBI Synonym Full Names:ets variant 4
NCBI Official Symbol:ETV4  
NCBI Official Synonym Symbols:E1AF; PEA3; E1A-F; PEAS3  
NCBI Protein Information:ETS translocation variant 4; adenovirus E1A enhancer-binding protein; polyomavirus enhancer activator 3 homolog; EWS protein/E1A enhancer binding protein chimera; ets variant gene 4 (E1A enhancer-binding protein, E1AF)
UniProt Protein Name:ETS translocation variant 4
UniProt Synonym Protein Names:Adenovirus E1A enhancer-binding protein; E1A-F; Polyomavirus enhancer activator 3 homolog; Protein PEA3
Protein Family:ETS translocation
UniProt Gene Name:ETV4  
UniProt Entry Name:ETV4_HUMAN
Anti-Pea3 / ETV4 Antibody (CAB5797)Western blot analysis of extracts of various cell lines, using Pea3 / ETV4 Rabbit pAb (CAB5797) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Anti-Pea3 / ETV4 Antibody (CAB5797)Immunohistochemistry of paraffin-embedded Human skin using Pea3 / ETV4 antibody (CAB5797) at dilution of 1:100 (40x lens).
Anti-Pea3 / ETV4 Antibody (CAB5797)Immunohistochemistry of paraffin-embedded Mouse skin using Pea3 / ETV4 antibody (CAB5797) at dilution of 1:100 (40x lens).
Anti-Pea3 / ETV4 Antibody (CAB5797)Immunohistochemistry of paraffin-embedded Rat skin using Pea3 / ETV4 antibody (CAB5797) at dilution of 1:100 (40x lens).
Anti-Pea3 / ETV4 Antibody (CAB5797)Immunofluorescence analysis of U-2 OS cells using Pea3 / ETV4 Rabbit pAb (CAB5797) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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