UniProt Protein Function: | FBXL20: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Role in neural transmission. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 17q12Cellular Component: cytoplasmBiological Process: behavioral fear response |
UniProt Protein Details: | |
NCBI Summary: | Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q96IG2 |
NCBI GenInfo Identifier: | 38503141 |
NCBI Gene ID: | 84961 |
NCBI Accession: | Q96IG2.2 |
UniProt Secondary Accession: | Q96IG2,Q38J52, A8K729 |
UniProt Related Accession: | Q96IG2 |
Molecular Weight: | 44,980 Da |
NCBI Full Name: | F-box/LRR-repeat protein 20 |
NCBI Synonym Full Names: | F-box and leucine-rich repeat protein 20 |
NCBI Official Symbol: | FBXL20Â Â |
NCBI Official Synonym Symbols: | Fbl2; Fbl20Â Â |
NCBI Protein Information: | F-box/LRR-repeat protein 20; F-box protein FBL2 |
UniProt Protein Name: | F-box/LRR-repeat protein 20 |
UniProt Synonym Protein Names: | F-box and leucine-rich repeat protein 20; F-box/LRR-repeat protein 2-like |
Protein Family: | F-box/LRR-repeat protein |
UniProt Gene Name: | FBXL20Â Â |
UniProt Entry Name: | FXL20_HUMAN |