Description

FITC Anti-Human CD49d Antibody [BU49]

The FITC Anti-Human CD49d Antibody (BU49) offered by AssayGenie is a vital tool for researchers delving into cellular interactions and immune responses. This fluorescently labeled antibody specifically targets the CD49d protein found on human cells, enabling precise detection and analysis in various experimental setups.CD49d, also known as integrin alpha-4, plays a crucial role in cell adhesion and migration, particularly in the immune system where it is involved in leukocyte trafficking and homing. The FITC Anti-Human CD49d Antibody (BU49) allows for the visualization and characterization of CD49d-expressing cells, aiding in the understanding of their function and behavior in health and disease.

Whether studying immune cell dynamics, inflammatory processes, or cell migration pathways, this antibody provides reliable and accurate results. Its compatibility with fluorescence-based assays makes it a versatile tool for immunology research, offering insights into diseases such as autoimmune disorders, inflammatory conditions, and cancer. Trust AssayGenie's FITC Anti-Human CD49d Antibody (BU49) to enhance your investigations into cellular mechanisms and immune responses.

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Product Title:	FITC Anti-Human CD49d Antibody [BU49]
SKU:	AGEL2807
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	BU49
Synonyms:	Integrin alpha-4;ITGA4;CD49 antigen-like family member D;Integrin alpha-IV;VLA-4 subunit alpha;CD49d;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	FITC
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P13612
Gene ID:	3676
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

FITC Anti-Human CD49d Antibody [BU49] (AGEL2807)

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Description