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FITC Anti-Mouse CD105 Antibody [MJ7/18] (AGEL2740)

Datasheet MSDS
SKU AGEL2740
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, κ
Clone MJ7/18
Conjugation FITC
€107 - €275

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Description

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FITC Anti-Mouse CD105 Antibody [MJ7/18]

The FITC Anti-Mouse CD105 Antibody (MJ7/18) offered by AssayGenie is an essential tool for researchers studying the CD105 protein in mouse models. CD105, also known as endoglin, is a cell surface marker involved in angiogenesis and vascular development. This antibody is directly conjugated with FITC, a fluorescent tag, allowing for easy visualization and detection of CD105 expression in tissues and cells.The MJ7/18 antibody is highly specific and sensitive, ensuring accurate results in various applications such as flow cytometry, immunofluorescence, and immunohistochemistry.

Its reactivity with mouse samples has been rigorously tested and validated, guaranteeing reliable performance in experimental settings. By targeting CD105, researchers can gain insights into processes like tumor angiogenesis, cardiovascular diseases, and tissue regeneration.Overall, the FITC Anti-Mouse CD105 Antibody (MJ7/18) from AssayGenie is a valuable tool for investigating the role of CD105 in various biological contexts, making it an indispensable asset for studies in vascular biology, oncology, and regenerative medicine.

Product Title:FITC Anti-Mouse CD105 Antibody [MJ7/18]
SKU:AGEL2740
Size:50 Tests, 100 Tests, 200 Tests
Clone No:MJ7/18
Synonyms:Endoglin;END;Eng;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q63961
Gene ID:13805
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
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