Description

FITC Anti-Mouse CD150 Antibody [TC15-12F12.2]

The FITC Anti-Mouse CD150 Antibody (TC15-12F12.2) is a specialized tool for researchers conducting studies involving CD150, a cell surface receptor with important functions in the immune system. This antibody, labeled with FITC for fluorescence-based detection, is specifically designed for use in mouse samples and is validated for applications such as flow cytometry and immunofluorescence.CD150, also known as signaling lymphocytic activation molecule (SLAM), is a crucial regulator of immune cell activation and differentiation. It is involved in modulating immune responses, particularly in the context of T and B cell interactions.

The anti-mouse CD150 antibody binds specifically to the CD150 protein, allowing for precise detection and analysis in different cell populations.Research involving CD150 is relevant in various fields, including immunology, infectious diseases, and vaccine development. Understanding the role of CD150 in immune cell communication and function can provide insights into immune system regulation and potential therapeutic targets. By using the FITC Anti-Mouse CD150 Antibody (TC15-12F12.2), researchers can further explore the intricate mechanisms of immune responses and potentially discover new strategies for combating diseases.

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Product Title:	FITC Anti-Mouse CD150 Antibody [TC15-12F12.2]
SKU:	AGEL2300
Size:	50 Tests, 100 Tests, 200 Tests
Clone No:	TC15-12F12.2
Synonyms:	Slam;Slamf1;CD 150;Signaling lymphocytic activation molecule;
Host Species:	Rat
Reactivity:	Mouse
Application:	FCM

Isotype:	Rat IgG2a, λ
Isotype Control:	FITC Rat IgG2a, λ Isotype Control[B39-4]
Form:	Liquid
Conjugation:	FITC
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	Q9QUM4
Gene ID:	27218
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

FITC Anti-Mouse CD150 Antibody [TC15-12F12.2] (AGEL2300)

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Description