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FITC Anti-Rat CD44H Antibody [OX-49] (AGEL2426)

Datasheet MSDS
SKU AGEL2426
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Rat
Host Species Mouse
Isotype Mouse IgG2a, κ
Clone OX-49
Conjugation FITC
€53 - €113

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Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Rat CD44H Antibody [OX-49]

The FITC Anti-Rat CD44H Antibody (OX-49) is a potent tool for researchers studying CD44H, a key cell surface marker associated with cell adhesion and migration. This antibody, generated specifically for use in rat samples, is developed to detect and quantify CD44H expression in various tissues and cell types, facilitating investigations into cell interactions, signaling pathways, and disease mechanisms.CD44H, a variant of the CD44 glycoprotein family, plays a vital role in cell-cell interactions, lymphocyte activation, and tumor metastasis.

Its diverse functions in cell adhesion and migration make it a pivotal molecule for understanding physiological processes and pathological conditions such as cancer and inflammation. The FITC Anti-Rat CD44H Antibody provides researchers with a precise tool to visualize and study CD44H expression patterns, aiding in the development of targeted therapies and diagnostic tools.

Product Title:FITC Anti-Rat CD44H Antibody [OX-49]
SKU:AGEL2426
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-49
Synonyms:Pgp-1; H-CAM; CD44s;CD44H;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26051
Gene ID:12505
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
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