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FITC Anti-Rat CD45 Antibody [OX-1] (AGEL2444)

Datasheet MSDS
SKU AGEL2444
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Rat
Host Species Mouse
Isotype Mouse IgG1, κ
Clone OX-1
Conjugation FITC
€53 - €113

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Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Rat CD45 Antibody [OX-1]

The FITC Anti-Rat CD45 Antibody (OX-1) is a crucial tool for researchers studying immune responses in rat models. This antibody, validated for immunofluorescence applications, specifically targets the CD45 protein on rat immune cells, enabling precise detection and analysis in various experimental settings. Whether investigating immune cell populations, studying inflammatory processes, or exploring immune system function in disease models, the FITC Anti-Rat CD45 Antibody (OX-1) offers researchers a reliable and efficient method for visualizing and understanding CD45 expression in rat samples.

CD45, a widely studied transmembrane protein present on leukocytes, plays a pivotal role in mediating immune responses and regulating cell activation. By targeting CD45 with the FITC-conjugated OX-1 antibody, researchers can gain valuable insights into the distribution, localization, and activation status of immune cells in rat tissues. This antibody's high specificity and sensitivity make it an ideal choice for fluorescence-based experiments aimed at investigating immune cell dynamics and function in various research contexts.

Product Title:FITC Anti-Rat CD45 Antibody [OX-1]
SKU:AGEL2444
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-1
Synonyms:Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04157
Gene ID:19265
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
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