Fiztasovimab Antibody is a research-grade biosimilar monoclonal antibody targeting Envelope glycoprotein B. It is a human IgG1, lambda2 antibody. Reactivity: Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5). Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Envelope glycoprotein B (gB) is a ~102 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Product Name:
Fiztasovimab Antibody
SKU:
GXBS00824
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
Envelope glycoprotein B
Isotype:
IgG1, lambda2
Host Species:
Human
Reactivity:
Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Applications:
ELISA, FCM, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
NPC21, NPC-21, NPC21, 2467411-25-0
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
