The FKBP1B Antibody (CAB16375) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding to the FKBP1B protein, researchers can effectively detect and study its expression in various cell types, making it a valuable tool for investigations in immunology, cell biology, and cancer research.FKBP1B is a member of the FK506-binding protein (FKBP) family, known for its involvement in protein folding and in modulating the activity of various proteins, including immune response regulators.
This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
FKBP1B Antibody
SKU:
CAB16375
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
OTK4, FKBP1L, PKBP1L, PPIase, FKBP12.6, FKBP1B
Positive Sample:
22Rv1, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm, Sarcoplasmic Reticulum.
Calculated MW:
12kDa
Observed MW:
13kDa
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
Purification Method
Affinity purification
Gene ID
2281
RRID
AB_2769481
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FKBP1B Rabbit pAb (CAB16375) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Immunohistochemistry analysis of paraffin-embedded Rat heart using FKBP1B Rabbit pAb (CAB16375) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Mouse heart using FKBP1B Rabbit pAb (CAB16375) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Immunofluorescence analysis of L929 cells using FKBP1B Rabbit pAb (CAB16375) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
