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[KO Validated] FXN/Frataxin Rabbit Polyclonal Antibody (CAB16688)

SKU:
CAB16688
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • KO Validated Antibodies 1 Anti-FXN / Frataxin Antibody CAB16688KO Validated
  • KO Validated Antibodies 1 Anti-FXN / Frataxin Antibody CAB16688KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] FXN/Frataxin Rabbit Polyclonal Antibody
SKU:CAB16688
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin (NP_000135.2).
Sequence:LRTD IDAT CTPR RASS NQRG LNQI WNVK KQSV YLMN LRKS GTLG HPGS LDET TYER LAEE TLDS LAEF FEDL ADKP YTFE DYDV SFGS GVLT VKLG GDLG TYVI NKQT PNKQ IWLS SPSS GPKR YDWT GKNW VYSH DGVS LHEL LAAE LTKA LKTK LDLS SLAY SGKD A
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:FA; X25; CyaY; FARR; FRDA; FXN / Frataxin
Positive Sample:K-562,U-87MG,Jurkat,Raji,DU-145,Mouse kidney,Mouse liver,Mouse heart
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion.
Calculated MW:23kDa
Observed MW:14kDa

This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:2395
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using FXN / Frataxin Rabbit pAb (CAB16688) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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