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Key Features

Ganitumab ELISA Kit (GXEL00089)

SKU GXEL00089
Product Type ELISA Kit
Assay Type Quantitative
Detection Method Colorimetric
Sensitivity 0.156 μg/ml
Range 0.31-5 μg/mL
Size 96T
Synonyms AMG 479, 905703-97-1
$1,162

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Description

Ganitumab ELISA Kit

The Ganitumab ELISA Kit (SKU: GXEL00089) is a quantitative sandwich ELISA designed for the accurate quantitative detection of Ganitumab across Plasma, Serum. With a working range of 0.31-5 μg/mL and a sensitivity of 0.156 μg/ml, the kit combines a simple protocol with dependable colorimetric read-out for confident quantification.

Ganitumab (AMG-479) is a mAb against IGF-IR which also inhibits binding of both IGF-1 and IGF-2 ligands to IGF-IR. The therapeutic value of AMG-479 was evaluated in several preclinical settings including androgen-dependent prostate cancer, and combined with androgen-deprivation therapy. Ganitumab was found to be most potent against VCaP xenografts when it was used in combination with complete androgen-deprivation therapy. After 4 weeks of treatment, tumor volume was reduced by 72% and growth suppression was maintained over 16 weeks of treatment. These findings suggested that the use of ganitumab in conjunction with androgen-deprivation therapy may be beneficial in the treatment of prostate cancer.

Backed by Assay Genie quality control and technical support, this Ganitumab ELISA Kit is an ideal tool for laboratories studying Ganitumab. Order the Ganitumab ELISA Kit from Assay Genie for dependable performance.

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