The GDF15 Monoclonal Antibody (CAB22097) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated using hybridoma technology, is highly specific to GDF15 and is suitable for use in applications such as Western blot, immunofluorescence, and immunohistochemistry.GDF15 is a protein associated with diverse functions including cell growth, inflammation, and metabolism. Elevated levels of GDF15 have been linked to conditions such as cancer, cardiovascular disease, and metabolic disorders, making it a promising biomarker for disease diagnosis and prognosis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
GDF15 Monoclonal Antibody
SKU:
CAB22097
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC55565
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
Purification Method
Affinity purification
Gene ID
9518
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GDF15 Rabbit mAb (CAB22097) at 1:2000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): Ramos Exposure time: 10s.
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