Description

GenieFluor 488 Anti-Human CD127/IL-7RA Antibody [A019D5]

The GenieFluor 488 Anti-Human CD127 (IL-7Ra) Antibody (A019D5) offered by AssayGenie is a cutting-edge tool designed for precise detection and analysis of the CD127 (IL-7Ra) protein in human samples. This highly specific antibody is raised using advanced techniques and is validated for various applications, including immunofluorescence and flow cytometry.CD127, also known as the interleukin-7 receptor alpha chain, plays a pivotal role in immune system regulation and is essential for the development and maintenance of T cells. The GenieFluor 488 Anti-Human CD127 (IL-7Ra) Antibody enables researchers to delve deeper into the function and expression levels of CD127 in various cell types, making it a valuable asset for studies in immunology, oncology, and autoimmune diseases.

With its superior sensitivity and specificity, this antibody is a powerful tool for investigating the role of CD127 in immune homeostasis, T cell development, and immune-related disorders. Researchers can depend on the GenieFluor 488 Anti-Human CD127 (IL-7Ra) Antibody to provide accurate and reliable results, ultimately advancing our understanding of immune responses and paving the way for innovative therapeutic strategies.

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Product Title:	GenieFluor 488 Anti-Human CD127/IL-7RA Antibody [A019D5]
SKU:	AGEL2278
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	A019D5
Synonyms:	Interleukin-7 receptor subunit alpha;IL-7RA;CDw127;CD127;IL-7Rα;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	Genie Fluor488
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P16871
Gene ID:	3575
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

GenieFluor 488 Anti-Human CD127/IL-7RA Antibody [A019D5] (AGEL2278)

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Description