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GenieFluor 488 Anti-Human CD25 Antibody [BC96] (AGEL2367)

Datasheet MSDS
SKU AGEL2367
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone BC96
Conjugation AF488
€113 - €413

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Description

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GenieFluor 488 Anti-Human CD25 Antibody [BC96]

The GenieFluor 488 Anti-Human CD25 Antibody (BC96) is a cutting-edge tool essential for research focusing on CD25, a key marker found on activated T cells and regulatory T cells. This antibody, specifically engineered for human samples, offers exceptional sensitivity and specificity in various experimental applications. By targeting the CD25 protein, this antibody enables precise detection and characterization of T cell subsets, facilitating in-depth analysis in immunology and cancer research studies.CD25, also known as interleukin-2 receptor alpha chain, plays a pivotal role in T cell activation and immune regulation, making it a critical target for investigating immune responses and tolerance mechanisms.

Understanding the expression and function of CD25 is fundamental in unraveling the complexities of immune cell dynamics in health and disease, particularly in conditions such as autoimmune disorders, infectious diseases, and cancer. The GenieFluor 488 Anti-Human CD25 Antibody (BC96) empowers researchers to explore these intricate processes and advance knowledge in immunological research and therapeutic development.

Product Title:GenieFluor 488 Anti-Human CD25 Antibody [BC96]
SKU:AGEL2367
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BC96
Synonyms:Interleukin-2 receptor subunit alpha;IL2RA;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;p55;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01589
Gene ID:3559
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.
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